How Resveratrol can be effective for Metabolic Syndrome?
Metabolic Syndrome and the effects using Resveratrol
Resveratrol is a simple and naturally effective way for Metabolic Syndrome to repair. Most people with heart disease and diabetes are insulin-resistant, which is a root cause of metabolic syndrome with symptoms like raised blood sugar, increased triglycerides, reduced HDL, heightened inflammation, and an increased risk of heart attack, stroke, and diabetes.
Diabetes and heart disease are intimately connected. Diabetics without heart disease have the same risk for heart attack as non-diabetics with established heart disease.
The first step in guarding against metabolic syndrome is to gauge the risk of insulin resistance through simple blood tests such as triglycerides, insulin, HDL, CRP, and DHEA.
Insulin resistance and inflammation can usually be reduced effectively without the need for prescription drugs by using the right nutritional supplement and lifestyle strategies.
An Effective Natural Supplement
Nutritional supplements that are effective for reducing insulin resistance include fish oil, chromium, white bean extract, DHEA, vitamin D, lipoic acid, magnesium, cinnamon, beta glucans, resveratrol, and polyphenols found in red wine, skin of grapes, dark berries, cocoa, green tea, and apples.
Resveratrol, a flavonoid found in grape skins and concentrated in red wine, has also attracted a good deal of research attention. Red wine, 355 mL or 12oz per day, has been found to improve insulin responses in people with diabetes. Resveratrol suppresses inflammatory mediators and powerfully inhibits enzymes that break down. In data extrapolated from animal studies, resveratrol doses of at least 20 mg/day are necessary to protect against heart disease. A glass of red wine (about 180 mL or 6 oz) averages just 500 mcg of resveratrol.
In addition, resveratrol content in red wines varies enormously depending on type of grape, soil characteristics, methods of barreling, etc., but averages around only 2.5 mg/L. The Wine Doctor resveratrol enhanced wine has 100 mL + per 750 mL. Non-drinkers and those seeking protection for a health can obtain resveratrol in our concentrated formula 50mL per day. flavonoids.
Although resveratrol has widely been studied for its potential health benefits, little is known about its metabolic effects in humans. Our aims were to determine whether the polyphenol resveratrol improves insulin sensitivity in type 2 diabetic patients and to gain some insight into the mechanism of its action. After an initial general examination (including blood chemistry), nineteen patients enrolled in the 4-week-long double-blind study were randomly assigned into two groups: a resveratrol group receiving oral 2 × 5 mg resveratrol and a control group receiving placebo.
Before and after the second and fourth weeks of the trial, insulin resistance/sensitivity, creatinine-normalised ortho-tyrosine level in urine samples (as a measure of oxidative stress), incretin levels and phosphorylated protein kinase B (pAkt):protein kinase B (Akt) ratio in platelets were assessed and statistically analysed. After the fourth week, resveratrol significantly decreased insulin resistance (homeostasis model of assessment for insulin resistance) and urinary ortho-tyrosine excretion, while it increased the pAkt:Akt ratio in platelets.
On the other hand, it had no effect on parameters that relate to β-cell function (i.e. homeostasis model of assessment of β-cell function). The present study shows for the first time that resveratrol improves insulin sensitivity in humans, which might be due to a resveratrol-induced decrease in oxidative stress that leads to a more efficient insulin signalling via the Akt pathway.
Resveratrol a powerful antioxidant supplement,and is also a useful strategy to curtail inflammatory responses and improve insulin responses.
To receive your daily dose of Resveratrol get The Wine Doctor, R.E.W. A glass a day, keeps the doctor away!